Result The membrane filtration avoided interference of media by using isopropyl myristate as solvent. 结果以十四烷酸异丙酯作溶剂,采用薄膜过滤法,可消除基质干扰。
Isopropyl myristate molecular gels and drug-loaded transdermal capability 十四酸异丙酯分子凝胶及其促进透皮性能研究
Methods: LC was prepared with lecithin of various purity as surfactant, isopropyl myristate as oil phase and anhydrous alcohol as co-surfactant. 方法:使用不同纯度的卵磷脂作为表面活性剂,无水乙醇为助表面活性剂,十四酸异丙酯为油相制备液晶。
The washing ability of surfactants can be quantitatively obtained by determining solubilization of surfactants on isopropyl myristate, which is called IPM. 通过测定表面活性剂对豆蔻酸异丙酯(IPM)的增溶能力,可以定量求出表面活性剂的洗涤能力,此方法称为IPM法。
When absorption promoter IPM ( isopropyl myristate) was co administered with the drugs, the parabolic relationship no longer existed. 渗透促进剂肉豆蔻酸异丙酯(IPM)加入到贴片中后,药物的脂溶性LogPc和其Kp间无抛物线关系。
Conclusion: 1% of Carbomer 940,67% of ethanol and isopropyl myristate were the optimum matrix of testosterone gel. 结论:以1.0%卡波姆940,67%的乙醇和肉豆蔻酸异丙酯为基质的处方最佳。
This systems are super-molecular configuration and have wide applied foreground in drug-carriers. The organogels which were formed by isopropyl myristate ( IPM) gelated by Span 60, glyceryl monostearate ( GMS) and glyceryl palmitate ( GTP) were studied. 本文研究了Span60、单硬脂酸甘油酯(GMS)、三棕榈酸甘油酯(GTP)在十四酸异丙酯(IPM)中形成的分子凝胶。
30% ethanol cooperates with 1% Isopropyl Myristate ( IPM) have the best effect on permeation of the patch. 30%乙醇和1%肉豆蔻酸异丙酯协同对α-细辛醚贴片的促渗效果最佳,透皮速率达到(20.67±1.33)μg。
Results showed that the penetration effect of betamethasone patches could be improved obviously with the co-effect of 20% mono-laurin, 6% isopropyl myristate and 10% oleic acid. 结果表明,20%单月桂酸甘油酯、6%肉豆蔻酸异丙酯和10%油酸协同作用对其贴片有良好的促渗效果。